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Edvotek Sickle Cell Gene Detection (DNA-based)

Sickle Cell Gene Detection (DNA-based) 2134037
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Item #: 2134037
Ships Directly from Manufacturer Typically Within 2-4 Weeks - Lead Times Vary

In this Sickle Cell Anemia experiment, your students will investigate the restriction enzyme that discriminates between HbA (normal) and HbS (disease) genes and perform a simulated test on a patient.

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About This Item

Description

Sickle Cell Anemia is a common genetic disease that causes long rods in red blood cells, giving them a "sickled" appearance. These cells get stuck in small capillaries of the blood stream leading to oxygen deprivation that causes pain and organ damage. Sickle Cell Anemia is caused by a single point mutation in the hemoglobin gene that results in a faulty protein.

Features

  • Discover how a single nucleotide mutation can profoundly affect a person’s health
  • Explore Mendelian genetics and the molecule methods used to identify sickle cell disease
  • Perform agarose gel electrophoresis to separate differently-sized DNA molecules
  • Load, run, analyze, and size control samples and samples from a family of three to identify mutations in their hemoglobin genes
  • For 8 Gels
Includes:
  • Instructions
  • Ready-to-Load QuickStrip DNA Samples
  • UltraSpec-Agarose
  • Electrophoresis Buffer (50X)
  • Practice Gel Loading Solution
  • FlashBlue DNA Stain
Specifications
Maximum Age: 18+
Maximum Grade Level: Grade 12 +
Allergens: Contains No Allergens
Grade Level: High School-College
Safety: Caution Icon. No Choking Hazard
SUOM Description: Each
Age Range: 12-22
Brand Name: Edvotek
Description: Sickle Cell GE Dectect DNAbase
Edvotek Sickle Cell Gene Detection (DNA-based)