Description

Models are powerful tools for teaching science as they provide useful simplifications of structures and processes, helping to make the unseen seen and the complex simple.

CRISPR is a revolutionary new genetic engineering technique that makes editing genomes easy and inexpensive. It is based on a type of immune system found in many types of prokaryote.

Using the kit, students first make 3-D models of the components of CRISPR - the enzyme Cas9 and guide RNAs. Next, they use these to see how CRISPR is used to edit a genome.

The model also shows how CRISPR can be used to control gene transcription and to knockout genes. In the process, they gain a good understanding of the CRISPR technique and its applications.

The Model Making Kit includes enough materials for students to assemble up to 5 paper models working cooperatively. The comprehensive Teacher Resource Guide included provides illustrated readings, activities, key vocabulary and an assessment, along with teaching opportunities for students to Engage, Explore, Explain, Extend and Evaluate their understanding of the concepts presented.